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姓名：张立

性别：男

职称：教授

学位：博士

专业：分析化学

电子邮箱：zhangli8@ncu.edu.cn

研究方向：纳米材料的制备、调控及生化/环境分析应用

电话：15070090148

教育工作经历：

2021.12-至今 59599aa美高梅 教授

2018.08-2019.08 纽约州立大学布法罗分校 访问学者

2014.12-2021.12 59599aa美高梅 副教授

2010.07-2014.12 59599aa美高梅 讲师

2005.09-2010.06 西南大学 博士 导师：黄承志教授

2001.09-2005.07 西南师范大学 本科

教学简介：

1、承担了《分析化学》、《仪器分析》、《分析化学实验》、《仪器分析实验》、《环境分析化学》等本科生和研究生课程的教学工作；

2、指导本科生开展科研训练及大学生创新创业训练计划项目；

3、主持完成一项江西省高等学校教学改革研究课题（JXJG-16-1-28）；

4、主持完成一项江西省学位与研究生教育教学改革研究项目（JXYJG-2016-014）；

5、在中文核心期刊发表教学改革论文两篇；

6、获59599aa美高梅授课质量优秀提名奖；

7、获59599aa美高梅第三届教师授课竞赛二等奖。

科研简介：

主要研究方向为纳米材料的制备、调控及生化/环境分析应用，包括不同形态、光电性能各异的碳纳米材料、金属纳米材料及有机框架材料的合成及修饰，在此基础上开拓纳米材料在环境检测、生物传感及疾病诊疗等领域的分析应用。以第一作者或通讯作者在Small, Chem. Eng. J., Anal. Chem., Chem. Commun., TrAC-Trends Anal. Chem., ACS Appl. Mater. Interfaces, Biosens. Bioelectron.等国际刊物上发表SCI论文40 余篇，其中SCI一区论文22篇、Nature Index论文6篇、ESI Top 1%高被引论文1 篇、卷首插画论文1 篇、影响因子大于10.0 的论文9篇。主持国家自然科学基金项目3 项、江西省杰出青年基金项目1项、江西省自然科学基金重点项目1 项、江西省自然科学基金青年及面上项目各1 项、江西省教育厅项目1项。担任ACS Sustainable Chemistry & Engineering、Journal of Hazardous Materials、Sensors and Actuators B: Chemical等学术期刊特邀审稿人。

科研项目:

社会兼职：

1、《Journal of Pharmaceutical Analysis》青年编委；

2、《分析试验室》青年编委；

3、《冶金分析》青年编委。

获奖情况：

1、功能化石墨烯的电催化和分析化学研究，江西省自然科学奖二等奖，江西省人民政府，2018年度，排名第二；

2、光散射纳米探针及其分析应用，重庆市自然科学奖一等奖，重庆市人民政府，2013年度，排名第四。

代表性论文及专利：

1. Li Zhang, Quan-Gen Tan, Sai-Jin Xiao, Gui-Ping Yang, Xin Liu, Qiong-Qing Zheng, Jia-Qi Fan, Ru-Ping Liang, Jian-Ding Qiu.* DNAzyme-derived aptamer reversely regulates the two types of enzymatic activities of covalent-organic frameworks for the colorimetric analysis of uranium, Analytical Chemistry, 2023, 95, 4703-4711. (SCI一区, Nature Index)

2. Li Zhang, Quan-Gen Tan, Sai-Jin Xiao, Gui-Ping Yang, Qiong-Qing Zheng, Chen Sun, Xiang-Lan Mao, Jia-Qi Fan, Ru-Ping Liang, Jian-Ding Qiu.* Reversed regulation effects of ssDNA on the mimetic oxidase and peroxidase activities of covalent organic frameworks, Small, 2023, 19, 202207798. (SCI一区)

3. Li Zhang, Jia-Qi Fan, Qiong-Qing Zheng, Sai-Jin Xiao, Cheng-Rong Zhang, Shun-Mo Yi, Xin Liu, Wei Jiang, Quan-Gen Tan, Ru-Ping Liang, Jian-Ding Qiu.* A 2D mesoporous hydrazone covalent organic framework for selective detection and ultrafast recovery of Au(III) from electronic waste, Chemical Engineering Journal, 2023, 454, 140212. (SCI一区)

4. Li Zhang, Quan-Gen Tan, Jia-Qi Fan, Chen Sun, Yu-Ting Luo, Ru-Ping Liang,* Jian-Ding Qiu.* Microfluidics for chiral separation of biomolecules, TrAC-Trends in Analytical Chemistry, 2023, 158, 116842. (SCI一区)

5. Xi-Rui Deng, A-Wei Hu, Sheng-Qian Hu, Wen-Li Yang, Chen Sun, Sai-Jin Xiao, Gui-Ping Yang, Qiong-Qing Zheng, Ru-Ping Liang, Li Zhang,* Jian-Ding Qiu.* An in-situ strategy to construct uracil-conjugated covalent organic frameworks with tunable fluorescence/recognition characteristics for sensitive and selective Mercury(II) detection, Analytica Chimica Acta, 2023, 1252, 341056. (SCI一区)

6. Sai-Jin Xiao, Ming-Yue Yuan, Ya-Di Shi, Meng-Ping Wang, Hui-Han Li, Li Zhang,* Jian-Ding Qiu.* Construction of covalent organic framework nanozymes with photo-enhanced hydrolase activities for colorimetric sensing of organophosphorus nerve agents, Analytica Chimica Acta, 2023, 1278, 341706. (SCI一区)

7. Sai Jin Xiao, An Ting Qiu, Hui Han Li, Meng Ping Wang, Li Zhang,* Kai Xin Guo, Jing Guo, Jian-Ding Qiu.* Simultaneous detection and separation of uranium based on a fluorescent amidoxime-functionalized covalent organic polymer, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2023, 289, 122182.

8. Gui-Ping Yang,# Xiao-Lin Meng,# Sai-Jin Xiao, Qiong-Qing Zheng, Quan-Gen Tan, Ru-Ping Liang, Li Zhang,* Pu Zhang,* Jian-Ding Qiu.* Construction of D-A-conjugated covalent organic frameworks with enhanced photodynamic, photothermal, and nanozymatic activities for efficient bacterial inhibition, ACS Applied Materials & Interfaces, 2022, 14, 28289-28300.

9. Jia-Qing Chen,# Qiong-Qing Zheng,# Sai-Jin Xiao, Li Zhang,* Ru-Ping Liang,* Gangfeng Ouyang, Jian-Ding Qiu*. Construction of two-dimensional fluorescent covalent organic framework nanosheets for the detection and removal of nitrophenols, Analytical Chemistry, 2022, 94, 2517-2526. (SCI一区, Nature Index)

10. Li Zhang, Gui-Ping Yang, Sai-Jin Xiao, Quan-Gen Tan, Qiong-Qing Zheng, Ru-Ping Liang, Jian-Ding Qiu*. Facile construction of covalent organic framework nanozyme for colorimetric detection of uranium, Small, 2021, 2102944. (SCI一区)

11. Li Zhang, Qiong-Qing Zheng, Sai-Jin Xiao, Jia-Qing Chen, Wei Jiang, Wei-Rong Cui, Gui-Ping Yang, Ru-Ping Liang, Jian-Ding Qiu*. Covalent organic frameworks constructed by flexible alkyl amines for efficient gold recovery from leaching solution of e-waste, Chemical Engineering Journal, 2021, 426, 131865. (SCI一区)

12. Li Zhang, Ming-Fang Hong, Jia-Qing Chen, Jie Peng, Ru-Ping Liang, Jian-Ding Qiu*. Regulation of multiple energy transfer processes in a simple nanosystem for sensitive telomerase detection, Analytica Chimica Acta, 2020, 1097, 135-143. (SCI一区)

13. Li Zhang, Jia-Qing Chen, Ming-Fang Hong, Ru-Ping Liang, Jian-Ding Qiu*. Facile synthesis of fluorescent tungsten oxide quantum dots for telomerase detection based on the inner filter effect, Analyst, 2020, 145, 2570-2579.

14. Sai Jin Xiao, Li Zhi Wang, Ming Yue Yuan, Xiao Huan Huang, Jian Hua Ding*, Li Zhang*. Peroxidase-mimetic and fenton-like activities of molybdenum oxide quantum dots, ChemistrySelect, 2020, 5, 10149-10155.

15. Li Zhang, Xiao-Rong Chen, Shao-Hua Wen, Ru-Ping Liang, Jian-Ding Qiu*. Optical sensors for inorganic arsenic detection, TrAC-Trends in Analytical Chemistry, 2019, 118, 869-879. (SCI一区)

16. Li Zhang, Jie Peng, Ming-Fang Hong, Jia-Qing Chen, Ru-Ping Liang, Jian-Ding Qiu*. Cobalt phosphide nanowires for fluorometric detection and in-situ imaging of telomerase activity via hybridization chain reactions, Microchimica Acta, 2019, 186, 309.

17. Li Zhang, Dong Peng, Ru-Ping Liang, Jian-Ding Qiu*. Graphene-based optical nanosensors for detection of heavy metal ions, TrAC-Trends in Analytical Chemistry, 2018, 102, 280-289. (SCI一区)

18. Li Zhang, Ming-Fang Hong, Jie Peng, Jia-Qing Chen, Ru-Ping Liang, Jian-Ding Qiu*. A sensitive assay of telomerase activity based on the controllable aggregation of quantum dots, Sensors & Actuators: B. Chemical, 2018, 277, 22-29. (SCI一区)

19. Li Zhang, Zhao-Wu Wang, Sai-Jin Xiao, Dong Peng, Jia-Qing Chen, Ru-Ping Liang, Jun Jiang*. Jian-Ding Qiu*, Fluorescent molybdenum oxide quantum dots and HgII synergistically accelerate cobalt porphyrin formation: a new strategy for trace HgII analysis, ACS Applied Nano Materials, 2018, 1, 1484-1491.

20. Li Zhang, Jie Peng, Ming-Fang Hong, Jia-Qing Chen, Ru-Ping Liang, Jian-Ding Qiu*. A facile graphene oxide-based fluorescent nanosensor for the in situ “turn-on” detection of telomerase activity, Analyst, 2018, 143, 2334-2341.

21. Li Zhang, Ming Fang Hong, Zhao Jun Chu, Han Xu, Shan Ping Wang, Xiao Jing Zhao, Sai Jin Xiao*. A new copper mediated on-off assay for alkaline phosphatase detection based on MoOx quantum dots, Microchemical Journal, 2018, 141, 170-175.

22. Li Zhang#, Xiu-Zhi Cheng#, LanKuang, Ai-Zhen Xu, Ru-Ping Liang, Jian-Ding Qiu#*, Simple and highly selective detection of arsenite based on the assembly induced fluorescence enhancement of DNA quantum dots, Biosensors and Bioelectronics，2017, 94, 701-706. (SCI一区)

23. Ting-Xiang Liu#, Li Zhang#, Ru-Ping Liang∗, Jian-Ding Qiu∗. Highly selective detection of disulfenylated proteins through adimedone-based fluorescent probe and application in cells, Sensors & Actuators: B. Chemical, 2017, 238, 257-263. (SCI一区)

24. Sai Jin Xiao, Xiao Jing Zhao, Zhao Jun Chu, Han Xu, Guo Qing Liu, Cheng Zhi Huang, Li Zhang*, New off–on sensor for captopril sensing based on photoluminescent MoOx quantum dots, ACS Omega, 2017, 2, 1666-1671.

25. Sai Jin Xiao, Zhao Jun Chu, Jun Zuo, Xiao Jing Zhao, Cheng Zhi Huang, Li Zhang*, Fluorescent carbon dots: facile synthesis at room temperature and its application for Fe2+ sensing, Journal of Nanoparticle Research, 2017, 19, 84.

26. Li Zhang, Wei Song, Ru-Ping Liang, Jian-Ding Qiu*, Simultaneous determination of protein kinase A and casein kinase II by dual-color peptide biomineralized metal nanoclusters, Analytical Chemistry, 2016, 88, 11460-11467. (SCI一区, Nature Index)

27. Sai Jin Xiao, Xiao Jing Zhao, Ping Ping Hu, Zhao Jun Chu, Cheng Zhi Huang, Li Zhang*. Highly photoluminescent molybdenum oxide quantum dots: One-pot synthesis and application in 2,4,6-trinitrotoluene determination, ACS Applied Materials & Interfaces, 2016, 8, 8184-8191.

28. Sai Jin Xiao, Xiao Jing Zhao, Jun Zuo, Hai Qing Huang, Li Zhang*. Highly photoluminescent MoOx quantum dots: Facile synthesis and application in off-on Pi sensing in lake water samples, Analytica Chimica Acta, 2016, 906, 148-155. (SCI一区)

29. Sai Jin Xiao, Jun Zuo, Xiao Feng Dong, Xiao Jing Zhao, Li Zhang*. Label-free and rapid detection of histidine-rich peptides in Saliva, Spectroscopy and Spectral Analysis, 2016, 36, 2906-2910.

30. Li Zhang, Dong Peng, Ru-Ping Liang, Jian-Ding Qiu*. Nitrogen-doped graphene quantum dots as a new catalyst accelerating the coordination reaction between Cadmium(II) and 5,10,15,20-tetrakis(1-methyl-4-pyridinio)porphyrin for Cadmium(II) sensing, Analytical Chemistry, 2015, 87, 10894-10901. (SCI一区, Nature Index)

31. Li Zhang, Dong Peng, Ru-Ping Liang, Jian-Ding Qiu*. Graphene quantum dots assembled with metalloporphyrins for “turn on” sensing of hydrogen peroxide and glucose, Chemistry-A European Journal, 2015, 21, 9343-9348.

32. Sai Jin Xiao, Jun Zuo, Zhi Qiang Zhu, Yong Zhong Ouyang, Xing Lei Zhang, Huan Wen Chen, Li Zhang*. Highly sensitive DNAzyme sensor for selective detection of trace uranium in ore and natural water samples, Sensors and Actuators B: Chemical, 2015, 210, 656-660. (SCI一区)

33. Li Zhang#, Zhi-Yi Zhang#, Ru-Ping Liang, Ya-Hua Li, Jian-Ding Qiu*. Boron-doped graphene quantum dots for selective glucose sensing based on the “abnormal” aggregation-induced photoluminescence enhancement, Analytical Chemistry, 2014, 86, 4423-4430. (SCI一区, ESI Top 1%, Nature Index)

34. Li Zhang, Sai Jin Xiao, Lin Ling Zheng, Yuan Fang Li, Cheng Zhi Huang*. Aptamer-mediated nanocomposites of semiconductor quantum dots and graphene oxide as well as their applications in intracellular imaging and targeted drug delivery, Journal of Materials Chemistry B, 2014, 2, 8558-8565.

35. Li Zhang, Ru-Ping Liang, Sai-Jin Xiao, Jian-Mei Bai, Lin-Ling Zheng, Lei Zhan, Xi-Juan Zhao, Jian-Ding Qiu*, Cheng-Zhi Huang*. DNA-templated Ag nanoclusters as fluorescent probes for sensing and intracellular imaging of hydroxyl radicals, Talanta, 2014, 118,339-347. (SCI一区)

36. Li Zhang, Zhong-Xia Wang, Ru-Ping Liang, Jian-Ding Qiu*. Easy design of colorimetric logic gates based on nonnatural base pairing and controlled assembly of gold nanoparticles, Langmuir, 2013, 29, 8929-8935.

37. Li Zhang, Yun-Mei Zhang, Ru-Ping Liang, Zhong-Xia Wang, Jian-Ding Qiu*. Colorimetric logic gates based on ion-dependent DNAzymes, The Journal of Physical Chemistry C, 2013, 117, 12352-12357.

38. Li Zhang, Li-Xia Fan, Ru-Ping Liang*, Jian-Ding Qiu*.Construction of biomimetic interface by layer-by-layer self-assembly technique for electrochemical amperometric immunosensing applications, Chinese Journal of Analytical Chemistry, 2013, 41, 1795-1800.

39. Li Zhang, Huanjun Chen, Jianfang Wang, Yuan Fang Li, Jian Wang, You Sang, Sai Jin Xiao, Lei Zhan, Cheng Zhi Huang*. Tetrakis(4-sulfonatophenyl)porphyrin-directed assembly of gold nanocrystals: Tailoring the plasmon coupling through controllable gap distances, Small, 2010, 6, 2001-2009. (SCI一区, Highlighted as Frontispiece)

40. Li Zhang, Shu Jun Zhen, You Sang, Jing Yun Li, Yi Wang, Lei Zhan, Li Peng, Jian Wang, Yuan Fang Li, Cheng Zhi Huang*. Controllable preparation of metal nanoparticle/carbon nanotube hybrids as efficient dark field light scattering agents for cell imaging, Chemical Communications, 2010, 46, 4303-4305. (Nature Index)

41. Li Zhang, Cheng Zhi Huang*, Yuan Fang Li, Qing Li. Morphology control and structural characterization of Au crystals: From twinned tabular crystals and single-crystalline nanoplates to multitwinned decahedra, Crystal Growth & Design, 2009, 9, 3211-3217.

42. Li Zhang, Cheng Zhi Huang*, Yuan Fang Li, Sai Jin Xiao, Jian Ping Xie. Label-free detection of sequence-specific DNA with multiwalled carbon nanotubes and their light scattering signals, Journal of Physical Chemistry B, 2008, 112, 7120-7122.

43. 张立，邓希锐，胡阿威，邱建丁，梁汝萍，一种含嘧啶基团的COFs 的一步制备方法及其在汞（II）检测中的应用，发明专利，中国，专利号：202210387560.1，授权日期：2023年5月26日。