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美高梅(59599aa)官方网站-Best App Store

姓名 庹浔

性别

职称 高级实验师

学位 博士

专业水生生物学

电子邮箱tuoxun@ncu.edu.cn

研究方向 生态毒理学

教育工作经历

2007年至今:59599aa美高梅化学化工学院,从事教学、科研工作。

2010.09~2015.07: 中国科学院大学,获博士学位

教学简介

负责全校本科生有机化学实验课程的管理工作。

科研简介

主要从事有关微囊藻毒素的毒理学研究以及外源性小分子物质与体内蛋白质结合特性的分析。

科研项目

  1. 国家自然科学基金地区项目:微囊藻毒素-LR(MC-LR)对大鼠肝脏脂代谢紊乱的蛋白质组学及计算机模拟研究,项目编号:31860153。

  2. 省自然科学基金面上项目:微囊藻毒素-LR未知靶点蛋白的筛选以及它们对哺乳动物毒性作用机制的研究,项目编号:20181BAB204003。

代表性论文及专利

1) Ma XL, Kuang L, Wang XW, Zhang ZH, Chen CL, Ding P, Chi BZ, Xu JY, Tuo X*. Investigation on the interaction of aromatic organophosphate flame retardants with human serum albumin via computer simulations, multispectroscopic techniques and cytotoxicity assay. International journal of biological macromolecules,2023,247: 125741

2) Zhou BJ, Zhou H, Xu LL, Cai RR, Chen CL, Chi BZ, Tuo X*. An insight into the interaction between Indisulam and human serum albumin: Spectroscopic method, computer simulation and in vitro cytotoxicity assay. Bioorganic Chemistry, 2022, 127:106017.

3) Huang XJ, Zhang SY, Li YS, Yang X, Li N, Zeng GF, Chen FP, Tuo X*. Insight into the binding characteristics of rutin and alcohol dehydrogenase: Based on the biochemical method, spectroscopic experimental and molecular model. Journal of Photochemistry and Photobiology B: Biology, 2022,228:112394.

4) Lv XL, Jiang Z, Zeng GF, Zhao SJ, Li N, Chen FP, Huang XJ, Yao J, Tuo X*. Comprehensive insights into the interactions of dicyclohexyl phthalate and its metabolite to human serum albumin. Food and Chemical Toxicology, 2021, 155:112407.

5) Chen FP, Zhou LK, Zhou BJ, Zhang SY, Ma XL, Zhou H, Tuo X*. Elucidation on the interaction between transferrin and ascorbic acid: A study based on spectroscopic analysis, molecular docking technology, and antioxidant evaluation. Journal of Molecular Liquids, 2022, 360:119413.

6) Li N, Yang X, Chen FP, Zeng GF, Zhou LK, Li XK, Tuo X*. Spectroscopic and in silico insight into the interaction between dicofol and human serum albumin. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 264:120277.

7) Liao TC, Zhang, Y, Huang XJ, Jiang Z, Tuo X*. Multi-spectroscopic and molecular docking studies of human serum albumin interactions with sulfametoxydiazine and sulfamonomethoxine. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 246:119000.