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姓名：郭生梅

性别：男

职称：副教授

学位：理学博士

专业：有机化学

邮箱：smguo@ncu.edu.cn

研究方向：有机磷化学，绿色有机合成

教育工作经历：

2012,9至今 59599aa美高梅

2008,9-2012,1 中科院兰州化学物理研究所，物理化学，博士。导师：黄汉民研究员

2005,9-2008,6 湖南师范大学， 有机化学，硕士。导师：李金恒教授

2017,1-2018,1 加州大学圣迭戈分校， 访问学者。导师：Guy Bertrand教授

教学简介：担任了本科生《有机化学》、《绿色化学》等多门核心理论课程和专业选修课程。

科研简介：主持国家自然科学基金2项，省自然科学基金1项。

代表性论文及专利：

1. Guo, S. M.; Li, S.; Yan, W. J.; Liang, Z. B.; Fu, Z. J.; Cai, H.* Environmentally sustainable production and application of acyl phosphates. Green Chemistry, 2020, 22 (21), 7343-7347.

2. Fu, Z. J.; Fu, Y. P.; Yin, J.; Hao, G. G.; Yi, X. Z.; Zhong, T. T.; Guo, S. M.; Cai, H.* Electrochemical strategies for N-cyanation of secondary amines and alpha C-cyanation of tertiary amines under transition metal-free conditions. Green Chemistry，2021, 23 (23), 9422-9427.

3. Fu, Z. J.; Yin, J.; He, D. D.; Yi, X. Z.; Guo, S. M.; Cai, H.* An electrochemical method for deborylative selenylation of arylboronic acids under metal- and oxidant-free conditions. Green Chemistry , 2022, 24 (1), 130-135.

4. Li, S.; Jie, K.; Yan, W. J.; Pan, Q. J.; Zhang, M.; Wang, Y. F.; Fu, Z. J.; Guo, S. M.*; Cai, H.* Selective C-C bond cleavage of amides fused to 8-aminoquinoline controlled by a catalyst and an oxidant. Chemical Communications, 2020, 56 (89), 13820-13823.

5. Guo, S. M.; Li, S.; Zhang, Z. B.; Yan, W. J.; Cai, H.* Electrochemical selenation of phosphonates and phosphine oxides. Tetrahedron Letters, 2020, 61 (10).

6. Huang, Z. J.; Liu, W.; Li, S.; Yang, Y. T.; Guo, S. M.*; Cai, H.* Potassium Carbonate Promoted Nucleophilic Addition of Alkenes with Phosphites. Synlett, 2020, 31 (13), 1295-1297.

7. Fu, Z. J.; Hao, G. G.; Fu, Y. P.; He, D. D.; Tuo, X.; Guo, S. M.; Cai, H.* Transition metal-free electrocatalytic halodeborylation of arylboronic acids with metal halides MX (X = I, Br) to synthesize aryl halides. Organic Chemistry Frontiers, 2020, 7 (3), 590-595.

8. Fu, Z. J.; Cao, X. H.; Wang, S. L.; Guo, S. M.; Cai, H.* Conversions of aryl carboxylic acids into aryl nitriles using multiple types of Cu-mediated decarboxylative cyanation under aerobic conditions. Organic & Biomolecular Chemistry, 2020, 18 (41), 8381-8385.

9. Fu, Z. J.; Jiang, Y. Q.; Wang, S. L.; Song, Y. Y.; Guo, S. M.; Cai, H.* Pd-Catalyzed Decarboxylative Ortho-Halogenation of Aryl Carboxylic Acids with Sodium Halide NaX Using Carboxyl as a Traceless Directing Group. Organic Letters, 2019, 21 (9), 3003-3007.

10. Guo, S. M.; Jie, K.; Huang, L.; Zhang, Z. B.; Wang, Y. F.; Fu, Z. J.; Cai, H.* Fe-Catalyzed Bisphosphorylation of Amino-2-en-1-ones with Trialkyl Phosphites. Synlett, 2019, 30 (9), 1090-1094.

11. Guo, S. M.; Jie, K.; Zhang, Z. B.; Fu, Z. J.; Cai, H.* Regioselective C3-Phosphonation of Free Indoles via Transition-Metal-Free Radical/Hydrolysis Cascade. European Journal of Organic Chemistry, 2019, 2019 (8), 1808-1814.

12. Guo, S. M.; Zhang, Z. B.; Xu, J. X.; Li, S.; Fu, Z. J.; Cai, H.* Acid and 1, 2-Dichloroethane Co-Promoted Substitution of the Amino Groups in Gramine and its Analogues with Trialkyl Phosphites. Chemistryselect, 2019, 4 (48), 14111-14113.

13. Wang, Y. F.; Yang, Y. J.; Jie, K.; Huang, L.; Guo, S. M.*; Cai, H.* Copper-Catalyzed C2 and C3 Phosphonation of Benzofuran and Benzothiophene with Trialkyl Phosphites. Chemcatchem, 2018, 10 (4), 716-719.

14. Huang, L.; Zhang, Z. B.; Jie, K.; Wang, Y. F.; Fu, Z. J.; Guo, S. M.*; Cai, H.* Nucleophile-controlled mono- and bis-phosphonation of amino-2-en-1-ones via catalyst-free C(sp(3))-N bond cleavage. Organic Chemistry Frontiers, 2018, 5 (24), 3548-3552.

15. Jie, K.; Wang, Y. F.; Huang, L.; Guo, S. M.*; Cai, H.* Convenient sulfonylation of imidazoles and triazoles using NFSI. Journal of Sulfur Chemistry, 2018, 39 (5), 465-471.

16. Fu, Z. J.; Jiang, Y. Q.; Jiang, L. G.; Li, Z. J.; Guo, S. M.*; Cai, H.* Cu-catalyzed decarboxylative iodination of aryl carboxylic acids with NaI: A practical entry to aryl iodides under aerobic conditions. Tetrahedron Letters, 2018, 59 (51), 4458-4461.

17. Gong, J. H.; Huang, L.; Deng, Q. D.; Jie, K.; Wang, Y. F.; Guo, S. M.*; Cai, H.* Metal-free phosphonation of benzoxazoles and benzothiazoles under oxidative conditions. Organic Chemistry Frontiers, 2017, 4 (9), 1781-1784.

18. Huang, L.; Gong, J. H.; Zhu, Z.; Wang, Y. F.; Guo, S. M.*; Cai, H.* Selective Phosphoramidation and Phosphonation of Benzoxazoles via Sequence Control. Organic Letters, 2017, 19 (9), 2242-2245.

19. Huang, L.; Zhu, Z.; Cao, T. H.; Lei, X. Y.; Gong, J. H.; Guo, S. M.*; Cai, H.* Rapid, Practical and Efficient Synthesis of Enol Phosphates from beta-Keto Esters and Phosphites. Chinese Journal of Organic Chemistry, 2017, 37 (6), 1571-1576.

20. Wang, Y. F.; Yang, Y. J.; Huang, L.; Jie, K.; Guo, S. M.*; Cai, H.* Iodine Catalyzed Kabachnik-Fields Reaction of Trialkyl Phosphites: Facile Access to Benzoxazine Containing Phosphorus. Chinese Journal of Organic Chemistry, 2017, 37 (12), 3220-3228.

21. Zhu, Z.; Wang, Y. F.; Yang, M. M.; Huang, L.; Gong, J. H.; Guo, S. M.*; Cai, H.* A Metal-Free Cross-Dehydrogenative Coupling Reaction of Amides to Access N-Alkylazoles. Synlett, 2016, 27 (19), 2705-2708.

22. Guo, S. M.; Gong, J. H.; Zhu, Z.; Yu, L. H.; Wang, Y. F.; Huang, L.; Cai, H.* Copper-catalyzed Phosphorylation of Coumarins with Trialkyl Phosphites. Chemistry Letters, 2016, 45 (7), 825-827.

23. Gong, J. J.; Zhu, Z.; Lu, L.; Guo, S. M.*; Cai, H.* Copper-Catalyzed Oxidative Amidation of Aryl Ketone and Its Derivatives to Form alpha-Keto Amides. Chinese Journal of Organic Chemistry, 2015, 35 (9), 1917-1922.

24. Guo, S. M.; Lu, L.; Gong, J. H.; Zhu, Z.; Xu, F.; Wei, Z. H.; Cai, H.* Copper-mediated tandem reaction of beta-ketoesters/ketones with tertiary amines for the synthesis of 2,3-dihydrofurans. Organic & Biomolecular Chemistry, 2015, 13 (15), 4426-4429.

25. Guo, S. M.; Zhu, Z.; Lu, L.; Zhang, W. B.; Gong, J. H.; Cai, H.* Metal-Free Csp(3)-N Bond Cleavage of Amides Using tert-Butyl Hydroperoxide as Oxidant. Synlett, 2015, 26 (4), 543-546.

26. Lu, L.; Xiong, Q. H.; Guo, S. M*.; He, T. Q.; Xu, F.; Gong, J. H.; Zhu, Z.; Cai, H.* Iodine-catalyzed C3-formylation of indoles via C-N bond cleavage of tertiary amines under aerobic conditions. Tetrahedron, 2015, 71 (22), 3637-3641.

27. Lu, L.; Guo, S. M.*; Xiong, Q. H.; Liu, S. Y.; Li, X.; Cai, H.* Iodine-Catalyzed C-N Cleavage of Tertiary Amines: Synthesis of Methylene-Bridged Bis-1,3-dicarbonyl Compounds. Synthesis, 2014, 46 (18), 2445-2450.

28. Guo, S. M.; Lu, L.; Cai, H.* Base-Promoted, Mild and Highly Efficient Conversion of Arylboronic Acids into Phenols with tert-Butyl Hydroperoxide. Synlett, 2013, 24 (13), 1712-1714.