Name: Li Lai-Sheng

Gender: Male

Job title: Professor

Email Address: lilaishengcn@163.com

Education and Work Experience：

2022.08--present: School of Chemistry and Chemical Engineering, Nanchang University, engaged in teaching and scientific research, Professor.

2007.02 -- 2009.07: School of Chemical Biopharmaceutical Engineering, Nanyang Technological University, Singapore, Postdoctoral fellow

1990.10 -- 2022.07: Center of Analysis and Testing, Nanchang University, engaged in teaching and scientific research, professor and doctoral supervisor.

2001.09~2004.06: Wuhan University, major in analytical chemistry major,  Doctoral degree

1987.09~1990.07: Yunnan University, major in organic chemistry major, Master's degree

1978.09~1981.07: Jiangxi Normal University of Science and Technology, major in chemistry major

Teaching：

Teaching of undergraduate courses such as Analytical Chemistry, Instrumental Analysis, University Chemistry and Modern Separation Technology, as well as postgraduate courses such as Modern Separation Science and Organic Spectrum Analysis. Cultivating master's and doctoral students, guiding undergraduate scientific research training and graduation thesis, achieving good teaching results.

Research fields:

Mainly engaged in separation science and technology, chiral drug analysis and modern spectral analysis. Presided over or participated in the completion of 15 national, provincial and ministerial projects. Published more than 110 research papers in Journal of Chromatography A, Food Chemistry, Journal of Agricultural and Food Chemistry, Talanta, Analytical and Bioanalytical Chemistry. 15 national invention patents have been authorized, and 1 college chemistry textbook has been edited. Research on New Methods of Extracting and Separating Components from Food and Traditional Chinese Medicine won the second prize certificate number of Jiangxi Natural Science (Z-07-2-04-02), achieved good scientific research results.

Research projects：

Presided over 15 national and provincial scientific research projects.

1. Preside over the project: Study on residue analysis method of chiral pesticide enantiomers in food based on preparation of new bridged cyclodextrin stationary phase，National natural science foundation of China(No. 31860469, 2019.01-2022.12)

2. Preside over the project: Preparation of ordered mesoporous silica gel stationary phase modified by cyclodextrin and its application in chiral drug analysis, National natural science foundation of China (No. 21165012, 2012.01-2015.12)

3. Study on the influence of flavonoids on citrinin synthesis by monascus and its regulation mechanism, National natural science foundation of China (No. 31671837, 2017.01-2020.12, rank second)

4. Preside over the project:Rapid detection of enantiomeric residues of chiral fungicides in fruits and vegetables based on novel bridged cyclodextrin stationary phase, The Open Project of State Key Laboratory of Food Science and Technology (No.SKLF-KF-201605, 2016.05-2018.05)

5. Preside over the project:Preparation and separation application of cyclodextrin organic-inorganic chiral mesoporous materials,Jiangxi Province Natural Science Foundation(No. 2010GZH0089, 2011.1-2012.12)

6. Preside over the project:Preparation and application of a novel chiral stationary phase of aromatic bridged Biscyclodextrin, Key projects of science and technology research of Jiangxi Provincial Department of Education(No. GJJ150019,2015.1-2016.12)

7. Preside over the project:Chiral analysis of urine of people exposed to benzene and benzene series based on targeted metabonomics, joint project (No. 202009140004, 2020.09-2022.12)

Awards and Honors：

Won the second prize of Jiangxi natural science (Certificate No.Z-07-2-04-02).

Director of Jiangxi Chemical and Chemical Society and Chromatographic Society, expert in evaluation of key disciplines in Jiangxi Province, editorial board of Chinese Journal of Analytical Laboratory.

Representative papers and patents：

[1] Shuang Yazhou ,Zhang Tianci ,Zhong Hui,Li Laisheng*.Simultaneous enantiomeric determination of multiple triazole fungicides in fruits and vegetables by chiral liquid chromatography/tandem mass spectrometry on a bridged bis(β-cyclodextrin)-bonded chiral stationary phase.Food Chemistry,2021,345:128842.

[2] Shuang Yazhou,Zhang Tianci,Li Laisheng*.Preparation of a stilbene diamido-bridged bis(beta-cyclodextrin)-bonded chiral stationary phase for enantioseparations of drugs and pesticides by high performance liquid chromatography.Journal of Chromatography A,2020,1614:460702.

[3] Shuang Yazhou,Liao Yuqin ,Zhang Tianci, Li Laisheng*.Preparation and evaluation of an ethylenediamine dicarboxyethyl diamido-bridged bis(beta-cyclodextrin)-bonded chiral stationary phase for high performance liquid chromatography. Journal of chromatography A,2020,1619:460937.

[4]. Zhong Hui, Zeng Qingli, Zhang Tianci, Huang Zhiqing, Li Laisheng*. Preparation and Evaluation of a Ferrocenediamide Bridge bis(beta-Cyclodextrin)-Bonded Chiral Stationary Phase for HPLC. Chromatographia, 2022, 85:589-603.

[5] Zeng Qingli, Zhong Hui, Zhang Tianci, Huang Zhiqin, Li Laisheng*. Preparation and evaluation of a perylenediimide bridged bis(beta-cyclodextrin) chiral stationary phase for HPLC. Analytical Science, 2022, 38:989-1002.

[6] Li Liang, Li Laisheng*, Jin Yanhong ,Shuang Yazhou,Wang Hui. Preparation of a teicoplanin-bonded chiral stationary phase for simultaneous determination of clenbuterol and salbutamol enantiomers in meat by LC-MS/MS. Microchemical Journal,2020,157:104925.

[7] Shuang Yazhou,Liao Yuqin,Wang Hui, Wang Yuanxing,LiLaisheng*. Preparation and evaluation of a triazole-bridged bis(beta-cyclodextrin)

-bonded chiral stationary phase for HPLC.Chirality,2020,32(2):168-184.

[8] Wang Hui, Shuang Yazhou , Zhang Tianci, Li Liang, Li Laisheng*.Preparation and evaluation of a cholesterol derivatized beta-cyclodextrin-bonded phase for achiral and chiral HPLC.Analytical Sciences,2020,36:687-695.

[9] Shuang Yazhou,Cao Zhigang, Zhang Tianci, Li Laisheng*. Enantiomeric Separation of Chiral Triazole Pesticides by a Mono-6-(4-Nitrophenyl)-Ureido

-beta-Cyclodextrin-Bonded Stationary Phase using High-Performance Liquid Chromatography(HPLC).Analytical Letters,2020,53(15):2481-2500.

[10] Li Liang,Wang Hui,Shuang Yazhou, Li Laisheng*.The preparation of a new 3,5-dichlorophenylcarbamated cellulose-bonded stationary phase and its application for the enantioseparation and determination of chiral fungicides by LC-MS/MS.Talanta,2019,202:494-506.

[11] Li Liang,Wang Hui,Jin Yongjiu,Shuang Yazhou,Li Laisheng*.Preparation of a new benzylureido-beta-cyclodextrin-based column and its application for the determination of phenylmercapturic acid and benzylmercapturic acid enantiomers in human urine by LC/MS/MS.Analytical and Bioanalytical Chemistry,2019,411(21):5465-5479.

[12] Li Liang,Cheng Biaoping,Zhou Rendan, Cao Zhigang, Zeng Chun, Li Laisheng*.Preparation and evaluation of a novel N-benzyl-phenethylamino-beta-cyclodextrin-bonded chiral stationary phase for HPLC.Talanta,2017,174:179-191.

[13] Li Laisheng*, Zhang Tianci, Zhong Hui, Shuang Yazhou, Li Liang, The preparation method and its application of azobenzamide-based bridged β-cyclodextrin chiral stationary phase. National invention patent number, ZL202011355555.X, authorized announcement date, June 14, 2022.

[14] Li Laisheng*, Zhong Hui, Zeng Qingli, Zhang Tianci, Shuang Yazhou, Li Liang. The preparation method and its application of pyridine diamide-bridged bis-β-cyclodextrin stationary phase. National invention patent number, ZL0211184374. X, authorized announcement date, May 25, 2022.

[15] Li Laisheng*, Zhong Hui, Zhang Tianci, Zeng Qingli, Bi-Asia, Li Liang. The preparation method and its application of diimide-based bridged bis-β-cyclodextrin stationary phase. National invention patent number, ZL202110559628, authorization announcement date, May 20, 2022.