Name: Jing Zheng

Gender: Male

Title: Associate Professor

Degree: Doctor

Major: Medicinal Chemistry

E-mail: zhengjing@ncu.edu.cn

Research interests: Construction of nitrogen heterocyclic compounds, organic reaction involving iodine

Educational work experience

2006.9-2010.6. Jiangxi University of Traditional Chinese Medicine, School of Pharmacy, Bachelor of Pharmacy.

2010.9-2013.6, Jinan University, School of Pharmacy, Master of Pharmaceutical Chemistry.

2013.9-2017.3, Zhejiang University, School of Pharmacy, Doctor of Pharmaceutical Chemistry.

2017.3-2021.12, Nanchang University, School of Environment and Chemical Engineering, Associate Professor and Master Tutor of Pharmaceutical Engineering.

2022.1 – Now, Nanchang University, School of Chemistry and Chemical Engineering, Associate Professor and Master Tutor of Pharmaceutical Engineering.

Teaching:

Undergraduate courses of pharmaceutical chemistry and drug synthesis reaction, the third prize of Nanchang University teaching Competition in 2021

Introduction to scientific research

(1) Transition metal-catalyzed olefin radical functionalization reaction

(2) Synthesis of nitrogen heterocyclic compounds catalyzed by iodine

(3) Electrocatalytic synthesis of heterocyclic compounds

Research projects：

1) Hosted the Jiangxi Provincial Natural Science Foundation Project, 20232BAB203017, Research and Application of Directed Halogenation Reaction based on Electrocatalysis, 2024.01-2025.12, 100000

2) Hosted the Youth Foundation of Natural Science Foundation of Jiangxi Province, 20224BAB211022, Inverse Maltensitic hydrofunctionalization of olefin and its application in the construction of nitrogen heterocycles, 2023.01-2024.12, 100000

3) Presided over the horizontal project: Synthesis of 1-pyrene sulfonyl chloride, 2022.07-2022.12, 53,200

4) Presided over horizontal projects: Cyanex272 and P-507 synthesis process development and pilot test guidance, 202277-2025.7, 1.06 million

5) Presided over the horizontal project: Application of precious metal Catalytic coupling Reaction in the synthesis of pharmaceutical intermediates, 2022.06-2024.6, 300,000

6) Hosted the Youth Foundation of National Natural Science Foundation of China, 21801114, Research on the controlled synthesis of nitrogen heterocyclic rings based on free radical hydrofunctional/series cyclization of olefin, 2019.01-2021.12, 260,000

7) Participate in the special project of Young Thousand Talents Plan of Jiangxi Province (1001-02102129), 2019.1-2025.12, with an appropriation of 5 million

Social part-time job

Awards and Honors：

1. Awarded as excellent class tutor for undergraduates from 2019 to 2020.

2. 2018-2020 Outstanding Communist Party Member of Nanchang University

3. Third prize of Nanchang University Teaching Competition in 2021

Representative papers and patents：

(1) Wu, Shitong; Cheng, Xi; Yao, Changguang; Yang, Weiran; Zheng, Jing, Synthesis of CF3, CF2H-Substituted, Epoxide-Fused Heterocycles with Prop-2-ynylsulfonium salts. Asian Journal of Organic. Chemistry. 2023, 12(4), e202300023

(2) Jing Zheng*, Hong Gu, Qinfang Chen and Weiran Yang, Access to thiazoline and spiro[indoline-3,3’- thiophene] scaffolds via a formal [3 + 2] annulation reaction of crotonate-derived sulfur ylides and β-ketothioamides. Organic & Biomolecular Chemistry, 2023, 21, 2069-2080

(3) Chen Zhang, Yufen Wang, Weiran Yang*, and Jing Zheng*, Biobased 2,5-Dimethyltetrahydrofuran as a Green Aprotic Ether Solvent. Organic Process Research & Development. 2022 26 (9), 2685-2693

(4) Zhongrong Meng, Qiongqiong Wang, Doudou Lu， Tingting Yue， Pu Ai, Hua Liu, Weiran Yang*, Jing Zheng*. Domino Annulation Reaction of Sulfur Ylides and Morita−Baylis−Hillman Carbonates of Isatins: Synthesis of Oxospiro[bicyclo[3.1.0]hexane-6,3′-indolin] Scaffolds. The Journal of Organic Chemistry. 2020, 85, 15026-15037.

(5) Jing Zheng*, Xiaojie He, Hong Xu, Hua Liu, Weiran Yang*, A formal [3 + 2] annulation reaction of propargyl sulfonium compounds and N-ylides: access to pyrrolo[2,1-a]quinolines, pyrrolo[2,1-a] phthalazines and indolizines. Organic & Biomolecular Chemistry, 2020, 18, 8867-8875.

(6) Qinfang Chen, Yihao Pan, Tingting Yue, Weiran Yang, Hua Liu, Jing Zheng*, [4 + 2]-Annulation of Prop-2-ynylsulfonium Salts and Isatoic Anhydrides: Access to 3‑Methylthio-4-quinolones. Organic Letters, 2020, 22, 6096-6100.

(7) Qinfang Chen, Yihao Pan, Dongxin Zhao, Weiran Yang, Jing Zheng*, Construct indeno[1,2-b]oxepine or ciscyclopropylacrylate by sulfur ylides, RSC Advances, 2020, 10, 21895-21906.

(8) Jing Zheng, Zhongrong Meng, Doudou Lu, Dongxin Zhao, Qinfang Chen, Weiran Yang*, Asian Journal of Organic Chemistry, 2019, 8, 1-5.

(9) Zhongrong Meng, Weiran Yang*, Jing Zheng*, [4 + 3]-Cycloaddition of aza-o-quinone methides and azomethine imines to make 1,2,4-triazepines, Tetrahedron Letters, 2019, 60, 1758-1762.

(10) Jifeng Qi, Jing Zheng, Sunliang Cui*, Fe(III)-Catalyzed Hydroallylation of Unactivated Alkenes with Morita−Baylis−Hillman Adducts, Organic Letters, 2018, 20, 1355-1358.

(11) Jifeng Qi#, Jing Zheng#, Sunliang Cui*, Facile synthesis of carbo- and heterocycles via Fe(III)-catalyzed alkene hydrofunctionalization, Organic Chemistry Frontiers, 2018, 5, 222~225.

(12) Yangyong Shen, Bo Huang, Jing Zheng, Chen Lin, Yu Liu, Sunliang Cui*, Csp−Csp3 Bond Formation via Iron(III)-Promoted Hydroalkynylation of Unactivated Alkenes, Organic Letters, 2017, 19, 1744-1747.

(13) Jing Zheng, JiFeng Qi, Sunliang Cui*, Fe-Catalyzed Olefin Hydroamination with Diazo Compounds for Hydrazone Synthesis, Organic Letters, 2016, 18(1), 128~131.

(14) Jing Zheng, Yan Zhang, Dahai Wang, Sunliang Cui*, Silver(I)-Mediated Phosphorylation/Cyclization Cascade of N-Cyanamide Alkenes for Divergent Access to Quinazolinones and Dihydroisoquinolinones, Organic Letters, 2016, 18(8), 1768~1771.

(15) Jing Zheng, ZiYang Deng, Yan Zhang, Sunliang Cui*, Copper-Catalyzed Divergent Trifluoromethylation/Cyclization of Unactivated Alkenes, Advanced Synthesis & Catalysis, 2016, 358(5), 746~751.

(16) Jing Zheng#, Dahai Wang#, Sunliang Cui*, Fe-Catalyzed Reductive Coupling of Unactivated Alkenes with β-Nitroalkenes, Organic Letters, 2015, 17(18): 4572-4575.

(17) Jing Zheng, Yan Zhang, Sunliang Cui*, Rh(III)-Catalyzed Selective Coupling of N-Methoxy-1H-indole-1-carboxamides and Aryl Boronic Acids, Organic Letters, 2014, 16(13), 3560~3563.

(18) Jing Zheng#, Lijuan Deng#, Minfeng Chen, Xuzhi Xiao, Shengwei Xiao, Cuiping Guo, Gaokeng Xiao, Liangliang Bai, Wencai Ye, Dongmei Zhang, Heru Chen*, Elaboration of thorough simplified vinca alkaloids as antimitotic agents based on pharmacophore similarity, European Journal Medicinal Chemistry, 2013, 65, 158~167.

(19) Zheng Jing, Xiao Xuzhi, Guo Cui-Ping, Chen He-Ru *, An efficient method for introducing formyl groups to indole rings, Chemical Research and Applications, 2013, 25 (5), 760-763.